Case Report
Extrapulmonary Small Cell Carcinoma of the Anal Canal: A Case Report and Review of the Literature
Table 1
Summary of reported cases of anal canal EPSCC.
| Author (yr) | | Demographic | Metastatic disease at presentation | Treatment | Clinical course |
| Alcindor et al. (2008) [9] | 1 | 45y M HIV+ | y | Chemoradiation, C/E, G-CSF | Primary responded, distant disease progressed, died 6 mo after dx | Doddi et al. (2009) [10] | 1 | 60y F | n | Chemoradiation, C/E | Primary responded, distant disease developed, died 18 mo after dx | Nakahara et al. (1993) [11] | 1 | 48y M HIV+ | n | radiation, APR, chemoradiation, C/E, G-CSF | Pelvic local recurrence after surgery, distant disease developed, patient committed suicide 3 mo after surgery | Meyer et al. (2007) [12] | 1 | 41y F | y | Chemoradiation, C/E | Partial response of primary, complete response of liver and lung metastasis, but new bone metastasis developed, died 10 mo after dx |
Boman et al. (1983) [8] | 13 | ns | 5y | ns | Median survival 2 mo after dx | 8n | 7 APR | 6 patients recurred and had median survival of 6 mo after surgery 1 patient with 5 yr survival | 1 radiation | Died 8 mo after treatment |
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Ns: not specified; APR: abdominoperineal resection; C/E: cisplatin and etoposide; G-CSF: granulocyte colony stimulating factor.
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