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Case Reports in Medicine
Volume 2012, Article ID 351275, 4 pages
http://dx.doi.org/10.1155/2012/351275
Case Report

Pathologic Rupture of the Spleen in Mantle-Cell-Type Non-Hodgkin’s Lymphoma

1Department of Internal Medicine, Nassau University Medical Center, East Meadow, NY 11554, USA
2Department of Infectious Disease, Nassau University Medical Center, East Meadow, NY 11554, USA
3Department of Pathology, Nassau University Medical Center, East Meadow, NY 11554, USA
4Department of Gastroenterology, Nassau University Medical Center, East Meadow, NY 11554, USA

Received 23 November 2011; Revised 26 January 2012; Accepted 30 January 2012

Academic Editor: Dianne L. Atkins

Copyright © 2012 Christopher B. Tan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mantle cell lymphoma (MCL) accounts for less than 10 percent of all non-Hodgkin’s lymphoma (NHL). Pathologic or spontaneous rupture of the spleen has been reported in patients with lymphoma; however only 5 cases have been reported in patients with MCL. Although splenomegaly occurs frequently in patients with MCL, spontaneous splenic rupture is rare. We present a case of a 51-year-old female with MCL, who presented to the medical emergency room with splenic rupture. This case illustrates that clinicians should be aware of the incidence and presentation of patients with MCL and spontaneous splenic rupture, as early detection and heightened suspicion may prevent potentially fatal outcomes.