Case Report

An Unusual Presentation of Tumor Lysis Syndrome in a Patient with Advanced Gastric Adenocarcinoma: Case Report and Literature Review

Table 5

Similarities and differences between chemotherapy-induced TLS in advanced gastric adenocarcinoma reported in 2008 and our case.

SimilaritiesDifferences

(i) Massive liver metastasis
(ii) Elevated pretreatment LDH
(iii) Large tumor burden
-Outcome of TLS: resolved
Characteristics2008 caseActual case
HistologyPoorly differentiatedModerately differentiated
Tumor extensionPrimary bulky tumor is presentPrimary tumor was not present (previously resected)
Pretreatment laboratory dataSlightly elevated serum uric acidā€”
Elevated serum phosphate
Host-related risk factors for developing TLSā€”Dehydration
Chemotherapy regimenCapecitabine and cisplatinOxaliplatin, leucovorin, floxuridine, and docetaxel
Onset of TLS after receiving chemotherapy3 days7 days

Reference: [37].