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Case Reports in Medicine
Volume 2012, Article ID 515691, 4 pages
http://dx.doi.org/10.1155/2012/515691
Case Report

Paget’s Disease of the Breast in a Patient with Amyopathic Dermatomyositis

1Department of Dermatology, Haydarpaşa Numune Teaching and Research Hospital, 34668 Istanbul, Turkey
2Department of Surgery, Haydarpaşa Numune Teaching and Research Hospital, 34668 Istanbul, Turkey
3Department of Internal Medicine, Haydarpaşa Numune Teaching and Research Hospital, 34668 Istanbul, Turkey

Received 8 March 2012; Revised 23 August 2012; Accepted 26 August 2012

Academic Editor: Jeffrey M. Weinberg

Copyright © 2012 Sirin Yasar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Amyopathic dermatomyositis (AD) can be a part of paraneoplastic syndrome of an underlying malignancy. Paget’s disease is a rare form of breast cancer. We present a very rare case of Paget’s disease associated with AD. Paget’s disease has been diagnosed in a patient with AD who is under surveillance of dermatology department. The patient has undergone central lumpectomy with removal of the nipple-areola complex and sentinel lymph node biopsy. Surgical margins after lumpectomy and sentinel node biopsy were negative. The whole breast irradiation was performed after surgery. The patient receives medical treatment for AD of which lesions regressed in 1 year during the follow-up period. This is a very rare case of Paget’s disease diagnosed in a patient with AD. Female patients with dermatomyositis have been absolutely recommended to undergo screening for breast and gynaecological malignancies. AD may be an early finding of primary or recurrent malignancy of the breast.