Radiation-Induced Peripheral Malignant Nerve Sheath Tumor Arising from Vestibular Schwannoma after Linac-Based Stereotactic Radiation Therapy: A Case Report and Review of Literatures

Table 1

The cases of malignant transformation of VS after stereotactic radiation.

Author	Age/sex	NF2	RT tech	Final pathology	Years to 2nd tumor
Thomsen et al., 2000 [3]	19/F	Y	SRS	Sarcoma	6
Baser et al., 2000 [4]	N/A	Y	SRS	3 MPNSTs; 1 malignant meningioma,; 1 malignant ependymoma; (de novo)	N/A
Ho and Kveton, 2002 [5]	14/F	Y	SRS	Rapid growth (no patho)	7 months
McEvoy and Kitchen, 2003 [6]	22/M	Y	SRS	Rapid growth (no patho)	2
Bari et al., 2002 [7]	28/F	Y	SRS	MPNST	4
Rowe et al., 2008 [8]	F	Y	SRS	Malignant glioma (de novo)	3
Carlson et al., 2010 [9]	25/F	Y	SRT	Rhabdosarcoma (de novo)	10
Husseini et al., 2011 [10]	20/M	Y	SRS	MPNST	5
Comey et al., 1998 [11]	50/M	N	SRS	Triton	5
Shamisa et al., 2001 [12]	57/F	N	SRS	GBM (de novo)	7.5
Hanabusa et al., 2001 [13]	51/F	N	SRS	Sarcoma	6 months
Shin et al., 2002 [14]	26/F	N	SRS	MPNST	6
Wilkinson et al., 2004 [15]	53/M	N	SRS	MPNST	4
Muracciole et al., 2004 [16]	61/F	N	SRS	Triton	6
Maire et al., 2006 [17]	N/A	N	SRT	MPNST	19
Balasubramaniam et al., 2007 [18]	64/F	N	SRT	GBM (de novo)	5
Yang et al., 2010 [19]	74/M	N	SRS	Sarcoma	6
Demetriades et al., 2010 [20]	37/M	N	SRS	MPNST	10
Akamatsu et al., 2010 [21]	67/F	N	SRS	MPNST	7.5
Our case 2011	34/F	N	SRT	MPNST	6