Case Report

A Case of Drug Reaction with Eosinophilia and Systemic Symptoms

Table 1

RegiSCAR criteria for the likelihood of DRESS syndrome.

NoYesUnknown

(1) Fever > 38.5°C−10−1
(2) Enlarged lymph nodes (>2 sites, >1 cm)010
(3) Atypical lymphocytes010
(4) Eosinophilia00
 0.7–1.49 × 109/L or 10–19.9%1
 >1.5 × 109/L or ≥20%2
(5) Skin rash00
 Extent > 50%010
 At least 2 of: edema, infiltration, purpura, scaling−110
 Biopsy suggestive of DRESS−100
(6) Internal organ involvement00
 One1
 2 or more2
(7) Resolution in >15 days−10−1
(8) At least 3 investigations negative for alternative cause010

Final score: <2 No case; 2-3 possible case, 4-5 probable case; >5 definite case.