A Case of Drug Reaction with Eosinophilia and Systemic Symptoms

Table 2

Naranjo score for the likelihood of an adverse drug reaction.

	Yes	No	Unknown
(1) Previous conclusive reports on this reaction	1
(2) Did the adverse event appear after suspected drug given?	2
(3) Did the adverse reaction improve when the drug was discontinued or a specific antagonist given?	1
(4) Did the adverse reaction appear when the drug was readministered?			0
(5) Are there alternative causes that could have caused the reaction?	−1
(6) Did the reaction reappear when a placebo was given?			0
(7) Was the drug detected in any body fluid in toxic concentrations?		0
(8) Was the reaction more severe when the dose was increased or less severe when decreased?		0
(9) Did the patient have a similar reaction to the same or similar drugs in any previous exposure?		0
(10) Was the adverse event confirmed by any objective evidence?	1

Final score: >9 Definite ADR; 5–8 probable ADR; 1–4 possible ADR; <0 doubtful ADR.