Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Medicine
Volume 2012, Article ID 736521, 5 pages
http://dx.doi.org/10.1155/2012/736521
Case Report

Add-on Lamotrigine Treatment for Subsyndromal Depression after Manic or Mixed States in Bipolar Disorder Improved the Quality of Life

1Kimura Hospital, 6-19 Higashi-Honcho, Chuo-Ku, Chiba, Chiba-shi 260-0004, Japan
2Department of Psychiatry, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan

Received 27 May 2012; Accepted 30 August 2012

Academic Editor: B. Carpiniello

Copyright © 2012 Katsumasa Muneoka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. L. L. Judd, H. S. Akiskal, P. J. Schettler et al., “A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder,” Archives of General Psychiatry, vol. 60, no. 3, pp. 261–269, 2003. View at Publisher · View at Google Scholar · View at Scopus
  2. L. L. Judd, H. S. Akiskal, P. J. Schettler et al., “The long-term natural history of the weekly symptomatic status of bipolar I disorder,” Archives of General Psychiatry, vol. 59, no. 6, pp. 530–537, 2002. View at Google Scholar · View at Scopus
  3. R. W. Kupka, L. L. Altshuler, W. A. Nolen et al., “Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder,” Bipolar Disorders, vol. 9, no. 5, pp. 531–535, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. J. F. Goldberg and M. Harrow, “Subjective life satisfaction and objective functional outcome in bipolar and unipolar mood disorders: a longitudinal analysis,” Journal of Affective Disorders, vol. 89, no. 1–3, pp. 79–89, 2005. View at Publisher · View at Google Scholar · View at Scopus
  5. A. R. Rosa, C. M. Bonnín, G. H. Vázquez et al., “Functional impairment in bipolar II disorder: is it as disabling as bipolar I?” Journal of Affective Disorders, vol. 127, no. 1–3, pp. 71–76, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. E. Vieta, R. de Arce, M. A. Jiménez-Arriero, A. Rodriguez, V. Balanzá, and S. Cobaleda, “Detection of subclinical depression in bipolar disorder: a cross-sectional, 4-month prospective follow-up study at community mental health services (SIN-DEPRES),” Journal of Clinical Psychiatry, vol. 71, no. 11, pp. 1465–1474, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. R. M. Post, G. S. Leverich, W. A. Nolen et al., “A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network,” Bipolar Disorders, vol. 5, no. 6, pp. 396–406, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. M. M. Sidor and G. M. MacQueen, “Antidepressants for the acute treatment of bipolar depression: a systematic review and meta-analysis,” Journal of Clinical Psychiatry, vol. 72, no. 2, pp. 156–167, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. M. A. Frye, G. Helleman, S. L. McElroy et al., “Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression,” American Journal of Psychiatry, vol. 166, no. 2, pp. 164–172, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. E. Vieta, J. Angst, C. Reed, J. Bertsch, and J. M. Haro, “Predictors of switching from mania to depression in a large observational study across Europe (EMBLEM),” Journal of Affective Disorders, vol. 118, no. 1–3, pp. 118–123, 2009. View at Publisher · View at Google Scholar · View at Scopus
  11. E. Vieta, J. Locklear, O. Günther et al., “Treatment options for bipolar depression: a systematic review of randomized, controlled trials,” Journal of Clinical Psychopharmacology, vol. 30, no. 5, pp. 579–590, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. J. R. Calabrese, P. E. Keck Jr., W. Macfadden et al., “A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression,” American Journal of Psychiatry, vol. 162, no. 7, pp. 1351–1360, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Tohen, E. Vieta, J. Calabrese et al., “Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression,” Archives of General Psychiatry, vol. 60, no. 11, pp. 1079–1088, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. C. L. Bowden, J. R. Calabrese, G. Sachs et al., “A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder,” Archives of General Psychiatry, vol. 60, no. 4, pp. 392–400, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. J. R. Calabrese, C. L. Bowden, G. Sachs et al., “A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar I disorder,” Journal of Clinical Psychiatry, vol. 64, no. 9, pp. 1013–1024, 2003. View at Google Scholar · View at Scopus
  16. D. Popovic, M. Reinares, J. M. Goikolea, C. M. Bonnin, A. Gonzalez-Pinto, and E. Vieta, “Polarity index of pharmacological agents used for maintenance treatment of bipolar disorder,” European Neuropsychopharmacology, vol. 22, no. 5, pp. 339–346, 2012. View at Google Scholar
  17. M. L. M. van der Loos, P. G. H. Mulder, E. G. T. M. Hartong et al., “Efficacy and safety of lamotrigine as add-on treatment to lithium in bipolar depression: a multicenter, double-blind, placebo-controlled trial,” Journal of Clinical Psychiatry, vol. 70, no. 2, pp. 223–231, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. J. F. Goldberg, C. L. Bowden, J. R. Calabrese et al., “Six-month prospective life charting of mood symptoms with lamotrigine monotherapy versus placebo in rapid cycling bipolar disorder,” Biological Psychiatry, vol. 63, no. 1, pp. 125–130, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. J. F. Goldberg, J. R. Calabrese, B. R. Saville et al., “Mood stabilization and destabilization during acute and continuation phase treatment for bipolar I disorder with lamotrigine or placebo,” Journal of Clinical Psychiatry, vol. 70, no. 9, pp. 1273–1280, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. J. R. Calabrese, C. L. Bowden, G. S. Sachs, J. A. Ascher, E. Monaghan, and G. D. Rudd, “A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression,” Journal of Clinical Psychiatry, vol. 60, no. 2, pp. 79–88, 1999. View at Google Scholar · View at Scopus
  21. J. R. Calabrese, R. F. Huffman, R. L. White et al., “Lamotrigine in the acute treatment of bipolar depression: results of five double-blind, placebo-controlled clinical trials,” Bipolar Disorders, vol. 10, no. 2, pp. 323–333, 2008. View at Publisher · View at Google Scholar · View at Scopus
  22. J. R. Geddes, J. R. Calabreso, and G. M. Goodwin, “Lamotrigine for treatment of bipolar depression: independent meta-analysis and meta-regression of individual patient data from five randomised trials,” British Journal of Psychiatry, vol. 194, no. 1, pp. 4–9, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. T. Sato, R. Bottlender, M. Sievers, and H. J. Möller, “Distinct seasonality of depressive episodes differentiates unipolar depressive patients with and without depressive mixed states,” Journal of Affective Disorders, vol. 90, no. 1, pp. 1–5, 2006. View at Publisher · View at Google Scholar · View at Scopus
  24. J. J. Rakofsky and B. W. Dunlop, “Treating nonspecific anxiety and anxiety disorders in patients with bipolar disorder: a review,” Journal of Clinical Psychiatry, vol. 72, no. 1, pp. 81–90, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Tohen, J. Calabrese, E. Vieta et al., “Effect of comorbid anxiety on treatment response in bipolar depression,” Journal of Affective Disorders, vol. 104, no. 1–3, pp. 137–146, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. A. González-Pinto, F. Mosquera, A. Palomino et al., “Increase in brain-derived neurotrophic factor in first episode psychotic patients after treatment with atypical antipsychotics,” International Clinical Psychopharmacology, vol. 25, no. 4, pp. 241–245, 2010. View at Publisher · View at Google Scholar · View at Scopus
  27. H. P. Blumberg, J. Kaufman, A. Martin et al., “Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder,” Archives of General Psychiatry, vol. 60, no. 12, pp. 1201–1208, 2003. View at Publisher · View at Google Scholar · View at Scopus
  28. L. C. Foland, L. L. Altshuler, C. A. Sugar et al., “Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium,” NeuroReport, vol. 19, no. 2, pp. 221–224, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. H. K. Manji, G. J. Moore, and G. Chen, “Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness,” Biological Psychiatry, vol. 48, no. 8, pp. 740–754, 2000. View at Publisher · View at Google Scholar · View at Scopus
  30. C. M. Bonnin, J. Sanchez-Moreno, A. Martinez-Aran et al., “Subthreshold symptoms in bipolar disorder: impact on neurocognition, quality of life and disability,” Journal of Affective Disorders, vol. 136, no. 3, pp. 650–659, 2012. View at Google Scholar
  31. K. E. Burdick, J. F. Goldberg, and M. Harrow, “Neurocognitive dysfunction and psychosocial outcome in patients with bipolar I disorder at 15 year follow-up,” Acta Psychiatrica Scandinavica, vol. 122, no. 6, pp. 499–506, 2010. View at Publisher · View at Google Scholar · View at Scopus
  32. M. Mur, M. J. Portella, A. Martínez-Arán, J. Pifarré, and E. Vieta, “Persistent neuropsychological deficit in euthymic bipolar patients: executive function as a core deficit,” Journal of Clinical Psychiatry, vol. 68, no. 7, pp. 1078–1086, 2007. View at Google Scholar · View at Scopus
  33. C. López-Jaramillo, J. Lopera-Vásquez, J. Ospina-Duque et al., “Lithium treatment effects on the neuropsychological functioning of patients with bipolar I disorder,” Journal of Clinical Psychiatry, vol. 71, no. 8, pp. 1055–1060, 2010. View at Publisher · View at Google Scholar · View at Scopus
  34. A. P. Wingo, T. S. Wingo, P. D. Harvey, and R. J. Baldessarini, “Effects of lithium on cognitive performance: a meta-analysis,” Journal of Clinical Psychiatry, vol. 70, no. 11, pp. 1588–1597, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. C. Daban, A. Martínez-Arán, C. Torrent et al., “Cognitive functioning in bipolar patients receiving lamotrigine: preliminary results,” Journal of Clinical Psychopharmacology, vol. 26, no. 2, pp. 178–181, 2006. View at Publisher · View at Google Scholar · View at Scopus