A Case of Microangiopathic Antiphospholipid-Associated Syndromes during Pregnancy: Review of the Literature

Table 1

Laboratory data (abnormal findings are bold).

	17W5D	21W1D	22W6D C/S	Postpartum (Day 14)	Normal range
Blood count
WBC (μL)	5200	6100	5600	5000	3000–8500
RBC (μL)	2.87	2.65	2.51	2.07	3.78–4.99 × 10^6
Hb (g/dL)	9.2	8.6	7.9	6.5	10.8–14.9
Ht (%)	27.3	25.6	23.4	19.9	35.6–45.4
Plt (μL)	168	144	55	133	150–361 × 10^3
Coagulation test
aPTT (%)		48.6	49.6	94.2	76–130
PT (%)		136.5	134.2	134.2	70–130
Fibrinogen (mg/dL)		441	414	206	200–400
FDP (μg/mL)		12.6	38.5	29.9	<5.0
D-dimer (μg/mL)		6.6	24.5	22.1	<1.0
Immunological data
CRP (mg/dL)	<0.3	0.54	1.78	<0.3	<0.30
C3 (mg/dL)	55	36	39	35	68–128
C4 (mg/dL)	14	16	17	17	13–36
CH50 (U/mL)	37.2	28.4	29.3	33.5	32.0–48.0
Anti-dsDNA Ab (IU/mL)	50	38	43	28	<12
Anti-ssDNA Ab (AU/mL)		560	800	412	<25
Anti-Sm Ab (index)	<5.0	<5.0	<5.0	<5.0	<7.0
ANA (index)	1280	640	640		<40
Serum chemistry
TP (g/dL)	5.5	4.4	3.9	3.7	6.7–8.3
AST (IU/L)	20	27	165	20	13–33
ALT (IU/L)	11	8	70	9	6–27
LDH (IU/L)	260	268	495	343	119–229
ALP (IU/L)	210	232	297	200	115–359
T-Bil (mg/dL)	0.4	0.4			0.3–1.2
BUN (mg/dL)	18	41	56	30	8–22
Creatinine (mg/dL)	0.8	1.9	3.3	2.3	0.4–0.7
Uric acid (mg/dL)	7.3	11.3	11.3	9.6	2.3–7.0
Blood pressure (mmHg)	121/78	150/80	160/95	154/84
Urine
Urinary protein (g/day)	2	8.1	4.4	9.1	0.03–0.12
Urinary sugar	Negative	Negative	Negative	Negative