Case Report
Lymphangitic Pulmonary Metastases in Castrate-Resistant Prostate Adenocarcinoma
Table 1
Previously reported cases of lymphangitic pulmonary metastasis of prostate cancer.
| Reference | Status of PC at time of lymphangitic spread | Initial pulmonary presentation | Lung biopsy | Outcome |
| Miseria et al. [2] | Hormone sensitive | Diffuse interstitial infiltrate with reticulonodular pattern | Done | Clearing of infiltrates with ADT | Rossi et al. [3] | Hormone sensitive | Bilateral multiple small nodules | Done | Given ADT, outcome not reported | K. S. Miller and J. M. Miller [4] | Hormone sensitive | Diffuse, bilateral, reticulonodular infiltrate | Done | Not reported | Cohen et al. [5] | Hormone sensitive | Bilateral interstitial infiltrates | Done | Received ADT followed by chemotherapy with radiographic improvement | Heffner et al. [6] | After failing first-line hormonal therapy with DES | Large bilateral effusions with interstitial infiltrate | Done | Second-line hormonal therapy given | Arriero et al. [7] | Hormone sensitive | Bilateral interstitial densities with perihilar predominance | Done | Improvement with ADT but suffered SCD of unknown cause 4 months later | Schwarz et al. [8] | Developed after failing first-line therapy | Diffuse infiltrations and nodularity | Done | Improvement after orchiectomy |
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ADT: androgen deprivation therapy, DES: diethylstilbestrol, SCD: sudden cardiac death.
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