Case Reports in Medicine / 2013 / Article / Fig 2

Case Report

Multifocal and Multicentric Glioblastoma with Leptomeningeal Gliomatosis: A Case Report and Review of the Literature

Figure 2

Photomicrographs displaying pathognomonic histopathological features of glioblastoma. (a) Microvascular proliferation with endothelial layer hyperplasia. (b) Areas of geographic necrosis are present. (c) Microscopic examination reveals a hypercellular neoplasm with large, hyperchromatic, pleomorphic cells with cerebellar granular layer cells on the left. (d) Mitotic figures are readily identified in a background of pleomorphic, hyperchromatic neoplastic cells. H&E; original magnification ×10 (a), ×10 (b), ×10 (c), and ×40 (d).

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