Report of a Case of Radiation-Induced New-Onset Vitiligo with Collective Review of Cases in the Literature of Radiation-Related Vitiligo

Table 1

Summary of cases of vitiligo following radiotherapy reported in the literature.

Sr. no.	Author	Number of cases	Cancer for which radiation was given	Preexisting vitiligo	Chemotherapy	Time to hypopigmentation after completion of radiotherapy; (months)	Reference
(1)	Pajonk et al.	1	Hodgkin’s disease	Yes	N/A	N/A	[6]
(2)	Polat et al.	1	Nasopharyngeal carcinoma	No	Cisplatin (concurrent)	2	[7]
(3)	Levine and Ribeiro	2	Breast cancer	Yes	N/A	N/A	[8]
(4)	Koo et al.	2	Breast cancer	Yes	Yes (details N/A)	7	[9]
			Breast cancer	Yes	Yes (details N/A)	8
(5)	Weitzen et al.	1	Breast cancer	Yes	Yes (Anthracycline based)	2	[10]
(6)	Roth	1	Melanoma	N/A	N/A	N/A	[11]
(7)	Munshi et al.	1	Breast cancer	Yes	Yes	6	[4]
(8)	Kim et al.	1	Thymoma	No	No	3	[12]
(9)	The authors	1	Breast cancer	No	Yes	9	N/A
Total cases including authors’ single case		11	Breast cancer: 7; Other cancers: 4	Preexisting vitiligo: 7; None: 4	Chemo-experienced: 7; Not available: 4	Median time to develop vitiligo at radiation site: 6 months (𝑛=7)