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Case Reports in Medicine
Volume 2013 (2013), Article ID 461409, 5 pages
Case Report

Adrenal Incidentalomas in Cancer Patients Are Not Always “Innocent”: A Case Report and Review of the Literature

1251 Airforce General Hospital, Medical Oncology Department, 3RD P. Kanellopoulou Street, Katehaki, 11725 Athens, Greece
2251 Airforce General Hospital, Medical Oncology Department, 2nd Department of Surgery, 3RD P. Kanellopoulou Street, Katehaki, 11725 Athens, Greece
3University of Athens, Department of Pathology, 75th Mikras Asias Street, Goudi, 11527 Athens, Greece

Received 12 January 2013; Revised 25 February 2013; Accepted 13 March 2013

Academic Editor: Christian Urban

Copyright © 2013 Panagiota Economopoulou et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Herein, we report an unusual case of a 78-year-old woman with synchronous presentation of sigmoid cancer and a nonfunctioning primary adrenal cortex carcinoma, who developed superior vena cava syndrome due to metastatic lymphadenopathy from the latter malignancy. Our case suggests that adrenal incidentalomas during initial staging evaluation after cancer diagnosis are not always “innocent” and should not be “a priori” considered incidental findings attributed to hyperplasia, adenoma or even a non life-threatening metastasis from the primary tumor. It also emphasizes the importance of a continuous assessment of patients with synchronous primary malignancies, in order to timely evaluate changes in clinical or biological behavior and administrate the appropriate treatment.