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Case Reports in Medicine
Volume 2013, Article ID 690591, 3 pages
http://dx.doi.org/10.1155/2013/690591
Case Report

Successful Treatment with Bosentan of Lower Extremity Ulcers in a Scleroderma Patient

Department of Dermatology, University Hospital, KU Leuven, Kapucijnenvoer 33, 3000 Leuven, Belgium

Received 20 December 2012; Accepted 14 March 2013

Academic Editor: Masahiro Kohzuki

Copyright © 2013 Alix Naert and Petra De Haes. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. K. Shanmugam, P. Price, C. E. Attinger, and V. D. Steen, “Lower extremity ulcers in systemic sclerosis: features and response to therapy,” International Journal of Rheumatology, vol. 2010, Article ID 747946, 8 pages, 2010. View at Publisher · View at Google Scholar
  2. A. Abou-Raya, S. Abou-Raya, and M. Helmii, “Statins: potentially useful in therapy of systemic sclerosis-related Raynaud's phenomenon and digital ulcers,” Journal of Rheumatology, vol. 35, no. 9, pp. 1801–1808, 2008. View at Google Scholar · View at Scopus
  3. D. J. Abraham, T. Krieg, J. Distler, and O. Distler, “Overview of pathogenesis of systemic sclerosis,” Rheumatology, vol. 48, pp. iii3–iii7, 2009. View at Google Scholar · View at Scopus
  4. J. H. Korn, M. Mayes, M. Matucci-Cerinic et al., “Digital ulcers in systemic sclerosis: prevention by treatment with bosentan, an oral endothelin receptor antagonist,” Arthritis and Rheumatism, vol. 50, no. 12, pp. 3985–3993, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Matucci-Cerinic, C. P. Denton, D. E. Furst et al., “Bosentan treatment of digital ulcers related to systemic sclerosis: results from the RAPIDS-2 randomised, double-blind, placebo-controlled trial,” Annals of the Rheumatic Diseases, vol. 70, no. 1, pp. 32–38, 2011. View at Publisher · View at Google Scholar · View at Scopus
  6. T. Taniguchi, Y. Asano, M. Hatano et al., “Effects of bosentan on nondigital ulcers in patients with systemic sclerosis,” British Journal of Dermatology, vol. 166, pp. 417–421, 2012. View at Publisher · View at Google Scholar
  7. I. Rösener and A. Rübben, “Behandlung eines Ulcus Cruris mit Bosentan bei einer Patientin mit progressiver systemischer Sklerodermie,” Hautarzt, vol. 58, pp. 392–393, 2007. View at Publisher · View at Google Scholar
  8. M. E. G. Ferreira and M. A. Scheinberg, “Successful treatment with bosentan of non-digital skin ulcers in severe scleroderma,” Annals of the Rheumatic Diseases, vol. 67, no. 12, pp. 1784–1785, 2008. View at Publisher · View at Google Scholar · View at Scopus