Lingual Leishmaniasis Presenting to Maxillofacial Surgery in UK with Successful Treatment with Miltefosine
Figure 2
Histopathology. (a) shows a low-power (×20) view of a cross section of the initial tongue biopsy stained with H and E and demonstrates the intense histiocyte-rich inflammatory infiltrate, sparing the squamous epithelium (right) and almost filling the corium extending deep into the soft tissues. (b) shows an oil immersion high-power view of the histiocytic infiltrate (×1000) stained with Giemsa and shows the histiocytes with many intracellular amastigote forms characterized by the “double-dot” sign (inset ×4 compared to the original). These are the Leishman-Donovan bodies.
