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Case Reports in Medicine
Volume 2014, Article ID 138963, 3 pages
http://dx.doi.org/10.1155/2014/138963
Case Report

The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma

1Department of Internal Medicine, Madigan Army Medical Center, 9040 Fitzsimmons Drive, Tacoma, WA 98431, USA
2Department of Pulmonary and Critical Care Medicine, Brooke Army Medical Center, 3851 Roger Brooke Drive No. 3600, San Antonio, TX 78219, USA
3Department of Pulmonary, Sleep and Critical Care Medicine, Madigan Army Medical Center, 9040 Fitzsimmons Drive, Tacoma, WA 98431, USA

Received 18 April 2014; Revised 17 July 2014; Accepted 21 July 2014; Published 12 August 2014

Academic Editor: Luis García-Marcos

Copyright © 2014 Evelyn M. Slaughter et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

This paper presents a case of hymenoptera venom anaphylaxis averted by omalizumab, a monoclonal antibody to IgE antibody. This case suggests a novel and unintentional effect of this therapy. Currently omalizumab is only FDA approved for the treatment of moderate-persistent allergic asthma. However case reports, such as ours have illustrated omalizumab’s efficacy in the treatment of a myriad immunologic and allergic diseases. These outcomes have broadened the understanding of omalizumab’s complex mechanism of action.