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Case Reports in Medicine
Volume 2014, Article ID 293063, 5 pages
Case Report

State of Oral Mucosa as an Additional Symptom in the Course of Primary Amyloidosis and Multiple Myeloma Disease

1Department of Oral Medicine and Periodontal Diseases, Medical University of Warsaw, ul. Miodowa 18, 00-246 Warsaw, Poland
2Department of Hematology, University Hospital in Cracow, ul. Kopernika 17, 31-501 Cracow, Poland
3Department and Clinic of Haematology, Oncology and Internal Medicine, Medical University of Warsaw, ul. Banach 1A, 02-097 Warsaw, Poland

Received 23 February 2014; Accepted 22 May 2014; Published 9 June 2014

Academic Editor: Mark E. Shaffrey

Copyright © 2014 Maciej R. Czerniuk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Multiple myeloma (myeloma multiplex (MM)) is a malignant non-Hodgkin’s lymphoma derived from B cell. Its essence is a malignant clone of plasma cells synthesizing growth of monoclonal immunoglobulin, which infiltrate the bone marrow, destroy the bone structure, and prevent the proper production of blood cells components. The paper presents a case of 62-year-old patient who developed symptoms in addition to neurological and haematological changes in the oral mucosa in the course of multiple myeloma. The treatment resulted in partial improvement. The authors wish to draw attention not only to nonspecificity and rarity of changes in the mouth which can meet the dentist but also to the complexity of the multidisciplinary therapy patients diagnosed with MM.