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| Author [Reference] | Gender/Age (Years) | Interval between AOSD diagnosis and ALF | Hepatotoxics prior to the onset of ALF | Baseline AOSD treatment before ALF | Treatment of ALF associated with AOSD | Underwent liver transplantation | Outcome |
|
Liese et al.
[3] | F/24 | Simultaneous | None | None | Extracorporeal liver support | Yes | Recovered |
|
Terán et al. [4] | M/23 | AOSD diagnosed after ALF when symptoms recurred | None | None | Supportive care | Yes | Recovered |
Taccone et al.
[5] | F/28 | 1 month | None | Prednisolone 8 mg/day | IV Methylprednisolone 500 mg and MARS | Yes | Recovered |
Mc Farlane et al.
[6] | M/21 | <1 month | Acetaminophen | Aspirin, Acetaminophen, | IV one pulse of Methyprednisolone 250 mg and then 20 mg IV BID | Yes | Recovered |
Yamanaka et al.
[7] | F/20 | 3 years | None | Cyclosporine, Prednisolone 15 mg/day | IV Methylprednisolone pulse 500 mg/day for 3 days | Yes | Recovered |
Ogata et al.
[8] | F/20 | 3 years | None | Prednisolone 15 mg/day | 2 days of pulse IV Methyl prednisolone 1 gm per day and then plasma exchange | Yes | Recovered |
Dino et al.
[9] | F/44 | Simultaneous | Aspirin 1.8 gram/day | None | IV MethylPrednisolone 1 gm/day for 2 days | Yes | Died |
Thabah et al.
[13] | F/29 | 10 days | Indomethacin | PO Prednisolone 40 mg/day and indomethacin | Steroids | No | Died |
Ott et al.
[14] | F/25 | Simultaneous | None | Prednisolone 16 mg/day for an undetermined rheumatic disease | UDCA | No | Recovered |
Linde et al.
[15] | F/39 | Simultaneous | Acetaminophen, Ibuprofen | NSAIDs | 3 days of IV Methyprednisolone 250 mg per day | No | Recovered |
Mylona et al.
[16] | M/46 | 2 months | None | Tapering dose of Prednisolone | Prednisolone 75 mg/day PO and Anakinra 100 mg/day PO | No | Recovered |
Nagashima et al.
[17] | F/51 | 3 years | Indomethacin | Oral betamethasone, methotrexate and Indomethacin | IV Pulse dexamethasone 100 mg/day and Cyclosporine 120 mg/day | No | Recovered |
| F/32 | 2 weeks | None | Prednisolone 50 mg/day and Cyclosporine 150 mg/day | 3 days of IV dexamethasone pulse therapy 120 mg/day, dexamethasone 5 mg/day cyclosporine | No | Recovered |
Hogan et al.
[18] | F/35 | Simultaneous | None | Sulfasalazine for rheumatic disease | 2 days of Methylprednisolone 80 mg IV every 8 hrs | No | Recovered |
Takami et al.
[19] | F/74 | Simultaneous | None | None | Prednisolone 30 mg/day | No | Recovered |
Schuster et al.
[20] | 50 y | Simultaneous | None | None | Prednisolone, methotrexate | No | Recovered |
Atsukawa et al.
[21] | 34 | NM | None | None | Prednisolone 40 mg/day | No | Recovered |
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