Case Report
Effectiveness of Bortezomib in Cardiac AL Amyloidosis: A Report of Two Cases
Table 2
Followup of case report 2.
| | January 2005 Basal | April 2005 after melp/pr 2 cycles | September 2006 after dex/thalidomide | January 2007 after 2 cycles of melp/dex (Figure 3) | July 2007 before bort/dex
| June 2008 after bort/dexa 6 cycles (Figure 4) | October 2008 (Figure 5) |
| Serum free light chains mg/dL (n.v. < 19.4 ) | 92 | 63 | 174 | 134 | 331 | 149 | 189 |
| / ratio (0.26–1.65) | 6.13 | 2.92 | 2.95 | 4.4 | 7.4 | 4.53 | 5.57 |
| BNP pg/mL (n.v. < 50) | | 81 | 2976 | 2480 | 3138 | 484 | 1292 |
| Troponin I ng/mL (n.v. < 0.06) | | 0.05 | 0.04 | 0.02 | 0.04 | 0.04 | 0.07 |
| IVS (mm) | 9 | 11 | 13 | 17 | | 12 | 14 |
| LVPPW (mm) | 9 | 10 | 13 | 15 | | 12 | 13 |
|
|
mel: melphalan; pr: prednisone; dex: dexamethasone; bort: bortezomib.
|