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Case Reports in Medicine
Volume 2014, Article ID 732192, 5 pages
Case Report

Collapsing Focal Segmental Glomerulosclerosis in a Patient with Systemic Lupus Erythematosus

Bronx Lebanon Hospital Center, Department of Medicine, 1650 Selwyn Avenue, Suit 10C, Bronx, NY 10457, USA

Received 31 May 2014; Revised 15 July 2014; Accepted 29 July 2014; Published 11 August 2014

Academic Editor: W. Zidek

Copyright © 2014 Hassan Tariq et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We present a case of a 36-year-old female from Ghana who presented with atypical chest pain and shortness of breath and was found to have bilateral transudative pleural effusion and trivial pericardial effusion. Further work-up revealed serological markers consistent with active lupus and negative HIV. She developed rapid deterioration of her renal function requiring dialysis. Her renal biopsy showed collapsing focal segmental glomerulosclerosis with diffuse mesangial proliferative glomerulonephritis, consistent with lupus nephritis class II along with tubular degenerative changes. She was started on high dose steroids and later on mycophenolate mofetil. Her renal function slowly recovered to baseline.