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Case Reports in Medicine
Volume 2015, Article ID 348204, 4 pages
Case Report

Cytomegalovirus Colitis with Common Variable Immunodeficiency and Crohn’s Disease

Department of Pathology, School of Medicine, Akdeniz University, Turkey

Received 25 November 2014; Accepted 9 February 2015

Academic Editor: Stephen A. Klotz

Copyright © 2015 Betül Ünal et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Here we present an eleven-year-old male patient who had been diagnosed with common variable immunodeficiency (CVID) three years ago due to recurrent sinopulmonary infections. Two years later he had been diagnosed with Crohn’s disease (CD) due to diarrhea episodes which were unresponsive to the treatment. Depending on the active gastrointestinal bleeding and perforation he underwent total colectomy. Despite immunoglobulin and antiviral therapies, general condition of patient deteriorated and he died in the postoperative seventh day. Laboratory analysis was seronegative. CMV inclusion containing cells were detected in postmortem biopsies taken from liver, lungs, and lymph nodes.