Markedly Elevated Carbamazepine-10,11-epoxide/Carbamazepine Ratio in a Fatal Carbamazepine Ingestion

Table 1

Serial serum carbamazepine levels drawn during hospital stay.

Date/time of laboratory collection	Serum carbamazepine level [4.0–12.0 mcg/mL]
Arrival	24.0 mcg/mL
Hospital day #1, evening	19.5 mcg/mL
Hospital day #1, night	18.7 mcg/mL
Hospital day #2, morning	19.3 mcg/mL
Hospital day #3, morning	10.5 mcg/mL
Hospital day #4, midday	12.8 mcg/mL
Hospital day #4, night	14.3 mcg/mL
Hospital day #5, morning	16.7 mcg/mL
Hospital day #5, evening	18.0 mcg/mL
Hospital day #5, night	19.9 mcg/mL
Hospital day #6, morning	20.4 mcg/mL

Serum carbamazepine analysis performed on a Beckman Coulter AU5800 Clinical Chemistry.
System using Beckman Coulter Emit 2000 Carbamazepine Assay.