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Case Reports in Medicine
Volume 2015, Article ID 390642, 4 pages
Case Report

Myocardial Infarction in a Premenopausal Woman on Leuprolide Therapy

Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, 1825 Eastchester Road, Bronx, NY 10461, USA

Received 26 April 2015; Revised 6 June 2015; Accepted 10 June 2015

Academic Editor: Masahiro Kohzuki

Copyright © 2015 Irving E. Perez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Premenopausal women with chest pain syndrome may have nonatherosclerotic coronary arteries with abnormal coronary flow. Estrogens have cardioprotective effect improving coronary vasodilatation. This case report discusses the consequences of leuprolide use by decreasing estrogen levels which led to acute myocardial infarction.