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Case Reports in Medicine
Volume 2015, Article ID 430869, 5 pages
Case Report

Memory Profiles after Unilateral Paramedian Thalamic Stroke Infarction: A Comparative Study

1Division of Molecular and Cognitive Neuroscience, Neuropsychology and Behavioural Neurology Unit, Faculty of Psychology and Interdisciplinary Platform Psychiatry and Psychology, University of Basel, 4055 Basel, Switzerland
2GSMN Neurocenter, Genolier Clinic, Genolier Swiss Medical Network, 1272 Genolier, Switzerland

Received 16 August 2015; Accepted 7 October 2015

Academic Editor: Eugen Trinka

Copyright © 2015 Antonio Carota et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We performed extensive neuropsychological assessment of two male patients (matched for age and educational level) with similar (localization and size) unilateral paramedian ischemic thalamic lesions (AB on the left and SD on the right). Both patients showed severe memory impairments as well as other cognitive deficits. In comparison to SD, AB showed severe impairment of executive functions and a more severe deficit of episodic/anterograde memory, especially in the verbal modality. The findings of this single case study suggest the possibility that the profile and severity of the executive dysfunction are determinant for the memory deficits and depend on from the side of the lesion. In addition to a material-side-specific (verbal versus visual) deficit hypothesis, the differential diencephalo-prefrontal contributions in mnestic-processing, in case of paramedian thalamic stroke, might also be explained in terms of their stage-specificity (encoding versus retrieval).