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Case Reports in Medicine
Volume 2015, Article ID 469136, 3 pages
http://dx.doi.org/10.1155/2015/469136
Case Report

Acute Renal Failure due to Leukaemic Infiltration in Chronic Lymphocytic Leukaemia

1Department of Gastroenterology, Bezmialem Vakif University, Vatan Street, Adnan Menderes Boulevard, 34093 Istanbul, Turkey
2Department of Internal Medicine, Bezmialem Vakif University, Vatan Street, Adnan Menderes Boulevard, 34093 Istanbul, Turkey
3Department of Internal Medicine, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
4Department of Family Medicine, Bagcilar Training and Research Hospital, Istanbul, Turkey
5Department of Nephrology, Bezmialem Vakif University, Vatan Street, Adnan Menderes Boulevard, 34093 Istanbul, Turkey

Received 9 March 2015; Revised 21 May 2015; Accepted 28 May 2015

Academic Editor: Masahiro Kohzuki

Copyright © 2015 Yusuf Kayar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Chronic lymphocytic leukemia (CLL) is a malignancy characterized by clonal proliferation and accumulation of B lymphocytes. Although leukaemic infiltration of the kidney is well recognized in CLL, acute renal failure (ARF) due to leukaemic infiltration is extremely rare. Here we present a case of ARF as the initial manifestation of CLL. The diagnosis was made by a kidney biopsy. Treatment with cyclophosphamide and prednisolone resulted in a completely improved renal function.