Case Report

Hemophagocytic Lymphohistiocytosis Complicating Dengue and Plasmodium vivax Coinfection

Table 1

Hematological and biochemical parameters.

Day 1Day 2Day 3Day 4Day 5Day 6Day 7Day 8

Hemoglobin (g%)13.47.89.39.410.312.514.012.9
Hematocrit (%)38.922.526.62629.437.340.039
WBC (×10³/cu mm)17.25.36.33.17.08.46.25.4
Neutrophils (%)25.945.553.770.384.17975
Lymphocytes (%)70.347.54025.38.71720
Platelets (×10³/cu mm)8062746978138258229
PT (seconds prolonged)76082
aPTT (seconds prolonged)7371222
Fibrinogen (150–350 mg/dL)160135225
ALT (<43 IU/L)1283684865546486343284291
AST (<43 IU/L)3764
ALP (<147 IU/L)1974
Bilirubin (<1.0 mg/dL)8.355.13.8
Albumin (3.5–5 g/dL)4.43.23.34.64.1
Urea (10–50 mg/dL)75524590393642
Creatinine (<1.2 mg/dL)10.90.41.00.80.80.9
Na+ (135–145 meq/L)129137135133135144
K+ (3–5 meq/L)5.64.34.03.24.5
Calcium (8–10 mg/dL)9.67.98.67.07.26.88.19.1
Amylase (30–110 U/L)175260230
Serum lipase (<50 IU/L)74.6
Creatinine kinase (<190 IU/L)16681355
Serum LDH (225–450 IU/L)12353560
Troponin T (by ICT)Negative Negative

PT, prothrombin time; aPTT, activated partial thromboplastin time; ALT, alanine transferase; AST, aspartate transferase; ALP, alkaline phosphatase.