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Case Reports in Medicine
Volume 2015, Article ID 742920, 4 pages
http://dx.doi.org/10.1155/2015/742920
Case Report

A Rare Cutaneous Adnexal Tumor: Malignant Proliferating Trichilemmal Tumor

1Department of Pathology, Medical School, Gaziosmanpasa University, 60300 Tokat, Turkey
2Department of Plastic and Reconstructive Surgery, Medical School, Ondokuz Mayıs University, 55270 Samsun, Turkey
3Department of Plastic and Reconstructive Surgery, Samsun Training and Research Hospital, 55100 Samsun, Turkey

Received 18 February 2015; Accepted 26 April 2015

Academic Editor: Jeffrey M. Weinberg

Copyright © 2015 Omer Alici et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Proliferating trichilemmal tumors (PTTs) are neoplasms derived from the outer root sheath of the hair follicle. These tumors, which commonly affect the scalp of elderly women, rarely demonstrate malignant transformation. Although invasion of the tumors into neighboring tissues and being accompanied with anaplasia and necrosis are accepted as findings of malignancy, histological features may not always be sufficient to identify these tumors. The clinical behavior of the tumor may be incompatible with its histological characteristics. Squamous-cell carcinoma should certainly be considered in differential diagnosis because of its similarity in morphological appearance with PTT. Immunostaining for CD34, P53, and Ki-67 is a useful adjuvant diagnostic method that can be used in differential diagnosis aside from morphological findings. In this study, we aimed to present the case of a 52-year-old female patient with clinicopathological features. We reported a low-grade malignant proliferating trichilemmal tumor in this patient and detected no relapse or metastasis in a 24-month period of follow-up.