Disseminated Gastric MALT Lymphoma with Monoclonal Gammopathy, t(11;18)(q21;q21), and Subsequent Development of T-Large Granular Lymphocytic Leukemia: A Case Report and Review of the Literature

Table 2

Reported cases of nongastric MALT lymphoma with monoclonal gammopathy.

Author/year	Age/sex	Primary MALT lymphoma	Chronic disease	Dissemination	Serum Ig	CD5	Genetic findings	Reference
Levine et al./1989	56/M	Eye	—	BM	IgMλ	−	T(11;18)	[16]
Ueda et al./1996	48/M	Liver	—	—	IgMκ	+	NA	[31]
Matsumoto et al./1996	74/F	Duodenum	—	—	IgAκ	−	NA	[32]
Nakata et al./1997	74/M	Eyes	—	—	IgMκ	−	NA	[33]
Mak et al./1998	62/M	Kidney	IgA NP	GI tract	IgMλ	−	NA	[34]
Sakai et al./2000	72	Ileum and colon	ITP, AIH	−	IgGκ	−	NA	[35]
Valdez et al./2001	50/M	Nasopharynx	—	BM	IgMκ	−	NA	[9]
	40/M	Eye and lung	—	—	IgMκ	−	NA
	60/F	Salivary gland	Gougerot syndrome	BM	IgMκ	−	NA
	61/F	Lung	—	PE, skin, and pericardium	IgMκ	−	NA
	74/M	Eye and pharynx	—	—	IgM, IgAκ	−	NA
Nagakawa et al./2002	61/M	Lung	—	BM	IgM	NA		[36]
Pachmann et al./2002	59/	Salivary gland	—	BM, LN, kidneys, liver	IgGλ	−	NA	[37]
Stokes et al./2002	72/F	Kidney	MPGN	—	IgMκ	−	NA	[38]
Thieblemont et al./2002	60/F	Thyroid	Hashimoto	—	IgGκ	−	NA	[39]
Saito et al./2004	65/F	Small bowel	GN and ascariasis	Ascites	IgMκ	NA	T(11;18)	[40]
Takasaki et al./2005	84/M	Lung	—	BM and PE	IgM	−	T(11;18)	[41]
Dalle et al./2006	49/M	Skin	Schnitzler syndrome	BM	IgMκ	+	NA	[42]
Gomyo et al./2007	67/F	Pleura	—	—	IgM	−	T(14:18)	[43]
Schulze et al./2007	75/M	Lung	—	BM	IgMκ	−	T(11;18)	[44]
Ohno and Isoda/2008	77/M	Lung	—	BM and PB	IgMκ	−	T(11;18)	[27]
Murota et al./2009	73/F	Skin	Schnitzler syndrome	BM	IgMκ	−	NA	[45]
Mikolaenko and Listinsky/2009	75/F	Salivary gland	RA	BM and lung	IgMλ	+	NA	[46]
Peces et al./2010	77/M	Kidney	Barrett’s esophagus	BM	IgMκ	−	NA	[47]
Mitchum et al./2010	46/M	Skin	—	BM	IgMκ	−	Bcl-2	[48]
Ikuta et al./2010	54/F	Colon	—	—	IgMκ	−	NA	[49]
Kim et al./2011	66/M	Small bowel	—	BM	IgMλ	−	NA	[50]
Lacoste et al./2013	74/F	Skin	Angiomatosis	BM and PB	IgMκ	+	NA	[51]
Wu et al./2014	70/M	Lung	—	—	IgAκ	−	NA	[30]
Chi et al./2014	72/F	Kidney	CKD	BM and PB	IgMκ	−	NA	[52]

NA: not available; NK: normal karyotype; PE: pleural effusion; BM: bone marrow; PB: peripheral blood; IgA NP: IgA nephropathy; ITP: idiopathic thrombocytopenic purpura; AIH:autoimmune hepatitis; MPGN: membranoproliferative glomerulonephritis; GN: glomerulonephritis; RA: rheumatoid arthritis; CKD: chronic kidney disease.