Amelioration of Sickle Cell Pain after Parathyroidectomy in Two Patients with Concurrent Hyperparathyroidism: An Interesting Finding

Table 1

Hb: hemoglobin, HPLC: high performance liquid chromatography, HbS: sickle cell hemoglobin, HbF: fetal hemoglobin, HbA and HbA2: adult hemoglobin, and PTH: parathyroid hormone.

	Case 1	Case 2
Age	59	26
Gender	Female	Male
Sickle cell genotype	Sickle cell-beta^+ thalassemia	Homozygous sickle cell (HBSS)
Hb (range 14–18 mg/dL)	9.8	7.1
Reticulocyte (range 0.5–2.9%)	2	5
Lactate dehydrogenase (range 135–225 U/L)	300	269
Total bilirubin (range 0.0–1.2 mg/dL)	1.2	0.7
HPLC
HbS%	65.4	14.5
HbF%	5.2	<1
HbA%	22.4	81.8
HbA2%	7	2.7
Calcium level (range 8.4–10.3 mg/dL)	12.7	11.8
Phosphate level (range 2.7–4.5 mg/dL)	1.9	9.1
PTH level (range 14–72 pg/mL)	147	4078
Vitamin D level (range 30–100 ng/mL)	23	20
Pathologic diagnosis	Parathyroid adenoma	Parathyroid hyperplasia