A Possible Association of Diindolylmethane with Pulmonary Embolism and Deep Venous Thrombosis

Table 1

Timeline of events.

Time	Event
10 years ago	The patient had a possible pulmonary embolism.
6 years ago	The patient ceased smoking tobacco.
1 year ago	The patient resumed smoking tobacco.; PSA was less than 3 ng/mL.
13 to 19 months ago	The patient used over-the-counter testosterone supplements.
4 months ago	Colonoscopy found a benign polyp.
3 to 4 months ago	The patient started using over-the-counter diindolylmethane.
5 weeks ago	The patient presented to the Emergency Department and was thought to have right sciatica.
3 weeks ago	The patient presented to the Emergency Department and was thought to have costochondritis.
Day 0	A lower extremity venous Doppler study found deep venous thromboembolism in his right lower extremity.; Computed tomography of the chest found bilateral pulmonary embolism with probable right middle lobe infarction.; The patient was hospitalized and started on anticoagulation.
5 months later	A lower extremity venous Doppler study found chronic deep venous thromboembolism in his right lower extremity.