Case Report
Quinine-Induced Disseminated Intravascular Coagulation
Table 1
Lab results on admission and most deranged value at discharge and six weeks after discharge.
| | Laboratory test (ref range & units) | On admission | Most deranged value during admission | At discharge | At 6 weeks after discharge |
| | White blood cells (4.0–10.8 K/UL) | 2.1 × 109 cells/L | 2.1 × 109 cells/L | 6.3 × 109 cells/L | 6.1 × 109 cells/L |
| | Haemoglobin (12.0–16.0 G/DL) | 15.8 gm/dL | 11.2 gm/dL | 11.9 gm/dL | 13.0 gm/dL |
| | Platelets (130–430 K/UL) | 233 × 109 cells/L | 8.1 × 109 cells/L | 130 × 109 cells/L | 268 × 109 cells/L |
| | Neutrophil (36–75%) | 35% | 35% | 58% | 58% |
| | Lymphocyte (20–50%) | 34% | 2% | 32% | 30% |
| | Blood urea nitrogen (6–20 MG/DL) | 21 mg/dL | 21 mg/dL | 8 mg/dL | 14 mg/dL |
| | Creatinine (0.5–1.1 MG/DL) | 1.2 mg/dL | 1.0 mg/dL | 1.0 mg/dL | 1.0 mg/dL |
| | Prothrombin time (PT) (12.0–14.7 seconds) | 19.4 seconds | 25.5 seconds | 14.3 seconds | 12.9 seconds |
| | International normalized ratio (INR) (<4.0) | 1.68 | 2.38 | 1.33 | 0.99 |
| | Partial thromboplastin time (aPTT) (23.3–35.7 seconds) | 49.9 seconds | 76.5 seconds | 25.6 seconds | 27.7 seconds |
| | D-dimer level (0–499 NG/ML) | >10,000.00 ng/dL | — | — | — |
| | Fibrinogen (193–473 MG) | 69 mg | 69 mg | 291 mg | 359 mg |
| | Lactate dehydrogenase (100–225 U/L) | 584 U/L | — | — | 145 U/L |
| | Haptoglobin (16–200 MG/DL) | 5.8 mg/dL | — | — | — |
| | Reticulocytes (0.5–2.0%) | 3.88% | — | — | — |
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