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Case Reports in Medicine
Volume 2016, Article ID 9462489, 4 pages
http://dx.doi.org/10.1155/2016/9462489
Case Report

A Case of Relapsing Polychondritis Initiating with Unexplained Fever

1Department of General Internal Medicine and Rheumatology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, Japan
2Department of Pathology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, Japan
3Department of Ophthalmology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, Japan
4Department of Otolaryngology, Nagasaki Medical Center, Kubara 2-1001-1, Omura 856-8562, Japan
5Department of Rheumatology, Nagasaki University Hospital, Sakamoto 1-7-1, Nagasaki 852-8501, Japan

Received 19 August 2015; Accepted 9 November 2015

Academic Editor: Thomas R. Chauncey

Copyright © 2016 Kosuke Hirayama et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Relapsing polychondritis (RP) is a rare autoimmune disease affecting the multiple organ system. Here, we describe a case of RP initially presenting with high fever. The patient was referred to our hospital for further examination of fever of unknown origin (FUO). On admission, the patient reported dry cough in addition to fever. On physical examination, her red, swollen ears were noted, attributed on histology to inflammation with auricular perichondritis. She was diagnosed with RP and treated with oral prednisone (50 mg/day); her fever and auricular inflammation resolved. The patient no longer reported cough and body temperature returned to normal and the elevated levels of C-reactive protein (CRP) were normalized. In this case, identification of the origin of fever was a challenge because of unspecific symptoms; however, awareness of the systemic manifestations of RP may lead to the prompt diagnosis and therapeutic intervention.