Spontaneous Tumour Lysis Syndrome in a Multiple Myeloma

Table 1

2004 Cairo-Bishop laboratory and clinical criteria for tumor lysis syndrome [4].

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Laboratory tumor lysis syndrome criterion for diagnosis

 Uric acid: ≥8 mg/dL or 25% increase from baseline

 Potassium: ≥6 mEq/L or 25% increase from baseline

 Phosphorus: ≥6,5 mg/dL (children), ≥4.5 mg/dL (adults), or 25% increase from baseline

 Calcium: ≤7 mg/dL, ≤25% decrease from baseline

Clinical tumor lysis syndrome criterion for diagnosis

 Creatinine ≥1.5 upper limit of normal (age > 12 years of age or age adjusted)

 Cardiac arrhythmia or sudden death

 Seizure

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