Case Report

Polyneuropathy as Novel Initial Manifestation in a Case of “Nonsecretory” POEMS Syndrome with Sjögren’s Syndrome

Table 1

Laboratory results.

VariableValue (normal range)

Hemoglobin, g/L164 (130–175)
White blood cell count, ×109/L6.43 (3.5–9.5)
Neutrophil, ×109/L4.12 (1.8–6.3)
Platelet count, ×109/L163 (125–350)
Creatinine, serum (SCr), umol/L90 (59–104)
Albumin, g/L35.5 (40–55)
Alanine transaminase (ALT), U/L29 (9–50)
Aspartate aminotransferase (AST), U/L24 (15–40)
Prothrombin time (PT), sec11.7 (9.6–12.2)
Activated partial thromboplastin time (APTT), sec27.4 (20.3–32.3)
D-Dimer, FEU mg/L0.60 (<0.55)
Immunoglobulin (Ig) G, g/L23.4 (7–16)
IgM, g/L0.58 (0.4–2.30)
IgA, g/L0.92 (0.7–4.0)
Serum kappa, mg/L3.31 (1.7–3.7)
Serum lambda, mg/L1.78 (0.90–2.10)
Serum kappa/lambda1.85 (1.35–2.65)
Urine kappa, mg/L2.10 (<4.10)
Urine lambda, mg/L1.69 (<7.50)
Urine kappa/lambda1.24 (0.70–4.5)
Creatine phosphokinase (CPK), U/L13 (39–308)
Probrain natriuretic peptide (BNP), pg/mL1393 (0–210)
Lactate dehydrogenase (LDH), U/L181 (135–225)
Testosterone, nmol/L4.21 (6.68–25.70)
Dehydroepiandrosterone, umol/L0.27 (1.91–13.4)
Thyroid stimulating hormone (TSH), mIU/L11.99 (0.34–5.60)
Free triiodothyronine (FT3), pmol/L2.40 (3.80–6.00)
Free thyroxine (FT4), pmol/L8.67 (7.86–21.10)
Free cortisol in urine, ug/24 h412.17 (30.15–129.13)
Serum calcium, mmol/L2.16 (2.15–2.50)
Beta 2-microglobulin, mg/L4.48 (0.9–3.10)
Vascular endothelial growth factor (VEGF), pg/mL>800 (0–142)
Cerebrospinal fluid (CSF) glucose, mmol/L4.28 (2.22–3.89)
Cerebrospinal fluid (CSF) protein, g/L1.13 (0.15–0.45)
Cerebrospinal fluid (CSF) chloridum, mmol/L126 (120–132)
Cerebrospinal fluid (CSF) Pandy’s test2+
Cerebrospinal fluid (CSF) white blood cell, 106/L0 (0–8)
Cerebrospinal fluid (CSF) red blood cell, 106/L2