Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Medicine
Volume 2017, Article ID 3192649, 6 pages
https://doi.org/10.1155/2017/3192649
Case Report

Rare Gingival Metastasis by Hepatocellular Carcinoma

Department of Medical Oncology, Jinling Hospital, Nanjing University Clinical School of Medicine, 305 East Zhongshan Road, Nanjing, Jiangsu Province, China

Correspondence should be addressed to Xiao-Yuan Chu; moc.361@000nauyoaixuhc

Received 18 January 2017; Accepted 26 February 2017; Published 12 March 2017

Academic Editor: Carl M. Allen

Copyright © 2017 Li-Jun Xue et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. Fitzmaurice, C. Allen, R. M. Barber et al., “Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic analysis for the global burden of disease study,” The Journal of the American Medical Association, 2016. View at Publisher · View at Google Scholar
  2. M. S. Grandhi, A. K. Kim, S. M. Ronnekleiv-Kelly, I. R. Kamel, M. A. Ghasebeh, and T. M. Pawlik, “Hepatocellular carcinoma: from diagnosis to treatment,” Surgical Oncology, vol. 25, no. 2, pp. 74–85, 2016. View at Publisher · View at Google Scholar · View at Scopus
  3. F. R. Pires, R. Sagarra, M. E. Pizzigatti Corrêa, C. M. Pereira, P. A. Vargas, and M. A. Lopes, “Oral metastasis of a hepatocellular carcinoma,” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, vol. 97, no. 3, pp. 359–368, 2004. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Hirshberg, P. Leibovich, and A. Buchner, “Metastases to the oral mucosa: analysis of 157 cases,” Journal of Oral Pathology and Medicine, vol. 22, no. 9, pp. 385–390, 1993. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Hirshberg, P. Leibovich, and A. Buchner, “Metastatic tumors to the jawbones: analysis of 390 cases,” Journal of Oral Pathology and Medicine, vol. 23, no. 8, pp. 337–341, 1994. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Hirshberg, A. Shnaiderman-Shapiro, I. Kaplan, and R. Berger, “Metastatic tumours to the oral cavity—pathogenesis and analysis of 673 cases,” Oral Oncology, vol. 44, no. 8, pp. 743–752, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. F. M. Lapeyrolerie and J. H. Manhold Jr., “Hepatoma metastatic to the gingiva. Report of a case,” Oral Surgery, Oral Medicine, Oral Pathology, vol. 18, no. 3, pp. 365–367, 1964. View at Publisher · View at Google Scholar · View at Scopus
  8. B. G. Radden and P. C. Reade, “Gingival metastasis from a hepatoma,” Oral Surgery, Oral Medicine, Oral Pathology, vol. 21, no. 5, pp. 621–625, 1966. View at Publisher · View at Google Scholar · View at Scopus
  9. B. A. Lund, E. H. Soule, and C. G. Moertel, “Hepatocellular carcinoma with metastasis to gingival mucosa: report of case,” Journal of Oral Surgery, vol. 28, no. 8, pp. 604–607, 1970. View at Google Scholar · View at Scopus
  10. D. Wedgwood, D. Rusen, and S. Balk, “Gingival metastasis from primary hepatocellular carcinoma. Report of a case,” Oral Surgery, Oral Medicine, Oral Pathology, vol. 47, no. 3, pp. 263–266, 1979. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Morishita and J. Fukuda, “Hepatocellular carcinoma metastatic to the maxillary incisal gingiva,” Journal of Oral and Maxillofacial Surgery, vol. 42, no. 12, pp. 812–815, 1984. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Kanazawa and K. Sato, “Gingival metastasis from primary hepatocellular carcinoma: report of a case and review of literature,” Journal of Oral and Maxillofacial Surgery, vol. 47, no. 9, pp. 987–990, 1989. View at Publisher · View at Google Scholar · View at Scopus
  13. F. Llanes, J. Sanz-Ortega, B. Suarez, and J. Sanz-Esponera, “Hepatocellular carcinomas diagnosed following metastasis to the oral cavity. Report of 2 cases,” Journal of Periodontology, vol. 67, no. 7, pp. 717–719, 1996. View at Publisher · View at Google Scholar · View at Scopus
  14. J. C. English III, C. Meyer, S. M. Lewey, and C. J. Zinn, “Gingival lesions and nasal obstruction in an immunosuppressed patient post-liver transplantation,” Cutis, vol. 65, no. 2, pp. 107–109, 2000. View at Google Scholar · View at Scopus
  15. E. Maiorano, A. Piattelli, and G. Favia, “Hepatocellular carcinoma metastatic to the oral mucosa: report of a case with multiple gingival localizations,” Journal of Periodontology, vol. 71, no. 4, pp. 641–645, 2000. View at Publisher · View at Google Scholar · View at Scopus
  16. F. Papa, S. Ferrara, L. Felicetta et al., “Mandibular metastatic hepatocellular carcinoma: report of a case involving severe and uncontrollable hemorrhage,” Anticancer Research, vol. 21, no. 3C, pp. 2121–2130, 2001. View at Google Scholar · View at Scopus
  17. J. R. Ramirez, J. Seoane, J. Montero, G. C. Esparza Gómez, and R. Cerero, “Isolated gingival metastasis from hepatocellular carcinoma mimicking a pyogenic granuloma,” Journal of Clinical Periodontology, vol. 30, no. 10, pp. 926–929, 2003. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Arai, T. Otsuka, K. Mori et al., “Metastasis of hepatocellular carcinoma to the supramaxillary gingiva and right ventricle,” Hepato-Gastroenterology, vol. 51, no. 58, pp. 1159–1161, 2004. View at Google Scholar · View at Scopus
  19. J. Seoane, I. Van Der Waal, R. I. F. Van Der Waal et al., “Metastatic tumours to the oral cavity: a survival study with a special focus on gingival metastases,” Journal of Clinical Periodontology, vol. 36, no. 6, pp. 488–492, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. J. C. Vigneul, O. Nouel, P. Klap, and M. Al Helali, “Metastatic hepatocellular carcinoma of the mandible,” Journal of Oral and Maxillofacial Surgery, vol. 40, no. 11, pp. 745–749, 1982. View at Publisher · View at Google Scholar · View at Scopus
  21. G. L. Ellis, J. L. Jensen, I. M. Reingold, and R. J. Barr, “Malignant neoplasms metastatic to gingivae,” Oral Surgery, Oral Medicine, Oral Pathology, vol. 44, no. 2, pp. 238–245, 1977. View at Publisher · View at Google Scholar · View at Scopus
  22. E. S. Chan and M. M. Yeh, “The use of immunohistochemistry in liver tumors,” Clinics in Liver Disease, vol. 14, no. 4, pp. 687–703, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. S. K. Lau, S. Prakash, S. A. Geller, and R. Alsabeh, “Comparative immunohistochemical profile of hepatocellular carcinoma, cholangiocarcinoma, and metastatic adenocarcinoma,” Human Pathology, vol. 33, no. 12, pp. 1175–1181, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. H. Kim, G. H. Choi, D. C. Na et al., “Human hepatocellular carcinomas with ‘Stemness’-related marker expression: keratin 19 expression and a poor prognosis,” Hepatology, vol. 54, no. 5, pp. 1707–1717, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. Y. Yoshida, T. Tsukuda, M. Yoshinari, and H. Sasaki, “Two cases of metastatic tumors to the mouth,” Nippon Koku Geka Gakkai Zasshi, vol. 22, no. 4, pp. 534–540, 1976. View at Google Scholar · View at Scopus
  26. Y. Kuga, A. Kitamura, I. Kusaba, J. Aketa, and N. Yamada, “Primary liver cancer with metastasis to gingiva: report of a case,” Nihon Koku Geka Gakkai Zasshi, vol. 22, no. 4, pp. 541–545, 1976. View at Google Scholar · View at Scopus
  27. K. Tokuyama, S. Koike, S. Takashima, S. Moriwaki, K. Uyama, and K. Jinno, “A case report of pedunculated hepatoma with very rare remote metastases after the resection,” Gan No Rinsho, vol. 30, no. 2, pp. 174–180, 1984. View at Google Scholar · View at Scopus
  28. S. J. Choi, Y. S. Kim, N. R. Kim et al., “A case of hepatocellular carcinoma with metastasis to gingival mucosa,” The Korean Journal of Hepatology, vol. 8, no. 4, pp. 495–499, 2002. View at Google Scholar · View at Scopus
  29. R. A. Alrumaih, A. A. Arian, A. A. Alhedyani, N. Al-Zaher, and M. A. Dababo, “Hepatocellular carcinoma first presenting as a tumor of the oral cavity,” Hematology/ Oncology and Stem Cell Therapy, vol. 8, no. 3, pp. 130–135, 2015. View at Publisher · View at Google Scholar · View at Scopus
  30. I. H. Heslop, “Secondary neoplasia of the jaws,” British Journal of Oral Surgery, vol. 2, no. 1, pp. 47–53, 1964. View at Publisher · View at Google Scholar · View at Scopus
  31. J. Appenzeller, S. Weitzner, and G. W. Long, “Hepatocellular carcinoma metastatic to the mandible: report of case and review of literature,” Journal of Oral Surgery, vol. 29, no. 9, pp. 668–671, 1971. View at Google Scholar · View at Scopus
  32. O. V. Batson, “The function of the vertebral veins and their role in the spread of metastases,” Annals of Surgery, vol. 112, no. 1, pp. 138–149, 1940. View at Google Scholar
  33. A. Chin, T. S. Liang, and A. J. Borislow, “Initial presentation of hepatocellular carcinoma as a mandibular mass: case report and review of the literature,” Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, vol. 86, no. 4, pp. 457–460, 1998. View at Publisher · View at Google Scholar · View at Scopus
  34. S.-J. Shin, J.-L. Roh, S.-H. Choi et al., “Metastatic carcinomas to the oral cavity and oropharynx,” Korean Journal of Pathology, vol. 46, no. 3, pp. 266–271, 2012. View at Publisher · View at Google Scholar · View at Scopus
  35. A. Greenstein, R. Witherspoon, F. Iqbal, and H. Coleman, “Hepatocellular carcinoma metastasis to the maxilla: a rare case,” Australian Dental Journal, vol. 58, no. 3, pp. 373–375, 2013. View at Publisher · View at Google Scholar · View at Scopus
  36. M. F. S. D. Rodrigues, C. M. Esteves, M. A. de Oliveira et al., “Fatal hepatocellular carcinoma presenting with oral metastasis in a patient with synchronic primary malignancies of prostate and liver,” Gerodontology, 2016. View at Publisher · View at Google Scholar · View at Scopus