Case Report

Rare Gingival Metastasis by Hepatocellular Carcinoma

Table 1

Cases of gingival metastasis by hepatocellular carcinoma with survival data in English literatures.

Case numberSex/ageGingival tumor as first signCancer differentiationUpper/lower jawDistant metastasis besides gingivalTherapyTruncated/overall survivalReference number

1M/56YesNAUpperLungs, pancreas, adrenal, LNsNA2/2 months[7]

2M/51YesUndifferentiationUpperLung, LNs, skin, peritoneumResection of gingival tumor2/2 months[8]

3M/52NoHigh differentiationLowerLungsHepatectomy, resection of gingival tumor15/39 months[9]

4M/56NoNAUpperNoneResection of gingival tumor1/6 months[10]

5M/64NoNAUpperLungs, adrenals, LNsTACE, resection of gingival tumor1/22 months[11]

6F/78YesModerate differentiationUpperSkull, lumbar vertebraePalliative excision of gingival tumor4/4 months[12]

7M/66YesNALowerNoneResection of gingival tumor5/5 months[13]

8M/44NoNAUpperNasal cavity, boneChemotherapy>3/24 months[14]

9M/70YesModerate differentiationUpper/lowerLungs, brainResection of gingival tumor, TACE8/8 months[15]

10M/55NoNALowerMandible and iliac bones, ribs, scapule, pleura, brainLiver tumor alcoholization, TACE, segmental resection of left mandible>8/92 months[16]

11M/65NoNAUpperNoneResection of gingival tumor, chemotherapy8/15 months[17]

12M/60NoModerate differentiationLowerLung, skin of multiple sitesPartial hepatectomy and TACE6/38 months[3]

13F/72NoModerate differentiationUpperCardiac muscle, abdominal LNTACE, radiotherapy in gingival tumor1/10 months[18]

14M/60NoPoor differentiationUpperLungs, brainChemotherapy, TACE, sorafenib, palliative resection of gingival tumor2/13 monthsPresent case

M, male; F, female; NA, not available; LN, lymph node; TACE, transarterial chemoembolization.
Truncated survival, the period from onset of oral metastasis to death.