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Case Reports in Medicine
Volume 2018, Article ID 1980638, 6 pages
Case Report

Posterior Reversible Encephalopathy Syndrome due to Hypomagnesemia: A Case Report and Literature Review

Department of Neurology, St. Josef Hospital, The Academic Hospital of Duisburg-Essen University, Mülheimer Strasse 83, 46045 Oberhausen, Germany

Correspondence should be addressed to Mohamad Almoussa; ed.rvl@assuomla.damahom

Received 8 September 2018; Accepted 30 October 2018; Published 29 November 2018

Academic Editor: Georgios D. Kotzalidis

Copyright © 2018 Mohamad Almoussa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Hypomagnesemia can cause various unspecific neurological complications, which can lead to diagnostic confusion. One of these complications is the posterior reversible encephalopathy syndrome (PRES), which is extremely uncommon and has been reported only twice in the English-language literature. Case presentation. We report the case of a 60-year-old man who presented with PRES involving only the cerebellar hemispheres and associated with hypomagnesemia. After excluding all the other possible etiologies of PRES, we started magnesium replacement therapy, which led to a remarkable but fluctuating clinical and chemical improvement. A full recovery with no need for further supplementation was achieved only after discontinuation of a proton pump inhibitor. Conclusions. This case highlights the role of magnesium in the pathophysiology of PRES; thereby, underlying hypomagnesemia should be considered in every PRES case with unclear etiology.