Disseminated Histoplasmosis with Miliary Histoplasmosis, Neurohistoplasmosis, and Histoplasma capsulatum Bacteremia in Probable Neurosarcoidosis
Table 1
Proposed diagnostic criteria for neurosarcoidosis [4].
Definite
Clinical presentation suggestive of neurosarcoidosis with exclusion of other possible diagnoses and the presence of positive nervous system histology
Probable
Clinical syndrome suggestive of neurosarcoidosis with laboratory support for central nervous system inflammation (elevated levels of cerebrospinal fluid protein and/or cells, the presence of oligoclonal bands, and/or magnetic resonance imaging evidence compatible with neurosarcoidosis) and exclusion of alternative diagnoses together with evidence for systemic sarcoidosis (either through positive histology, including Kveim test and/or at least two indirect indicators from gallium scan, chest imaging, and serum angiotensin converting enzyme)
Possible
Clinical presentation suggestive of neurosarcoidosis with exclusion of alternative diagnoses where the above criteria are not met