The Role of Adjuvant Radiotherapy for a Case of Primary Breast Sarcoma: A Plan Comparison between Three Modern Techniques and a Review of the Literature

Table 1

DVH parameters for PTV and OAR for each investigated technique, together with planning objectives.

Region of interest	Index	3D-CRT PB	3D-CRT AAA	IMRT AAA	RA AAA	Planning objective
PTV66	D95% (Gy)	63.5	63.2	63.0	65.5	≥62.7
	D5% (Gy)	70.0	70	68.0	70.0	≤70.6
	Dmean (Gy)	67.0	66.3	66.0	67.8	≈66.0
	CI	0.94	0.92	0.96	0.99	=1
	HI	0.10	0.10	0.07	0.07	=0
PTV50	D95% (Gy)	47.5	48.0	48.2	47.9	≥47.5
	D5% (Gy)	66.9	65.8	57.6	60.2	≤53.5
	Dmean (Gy)	55.7	55.7	51.5	53.3	≈50
	CI	0.92	0.94	0.96	0.95	=1
	HI	0.38	0.35	0.12	0.22	=0
Heart	V30 Gy (%)	11.0	13.0	10.1	15.4	≤46
	Dmean (Gy)	8.1	8.4	17.7	19.3	≤26
Left lung	V20 Gy (%)	21.0	21.2	18.0	17.4	≤20–30
	Dmean (Gy)	12.5	12.5	13.6	14.3	≤15
Right lung	D10% (Gy)	1.6	1.3	7.5	16.3	—
	D50% (Gy)	0.55	0.35	3.2	8.3	—
	Dmean (Gy)	0.81	0.80	4.0	9.6	—

3D-CRT = 3D conformal radiotherapy; IMRT = intensity-modulated radiotherapy; RA = RapidArc; D95% and D5% = doses received by the 95% and the 5% of PTV volume; D_mean = mean dose to the structure; V30 and V20 Gy = volumes of the structure receiving 30 Gy and 20 Gy; D10% and D50% = doses received by the 10% and 50% of the structure; CI = conformity index; HI = homogeneity index.