Case Report
Autoimmune Limbic Encephalitis in a Patient with Acute Encephalopathy and Hyponatremia
| Parameter | Result | Reference range |
| Blood/serum studies | Hemoglobin | 12.9 g/dL | 11.7–16.5 g/dL | Hematocrit | 38.7% | 35.7–45.8% | WBC count | 10.5 k/mm3 | 4–11 k/mm3 | Platelet count | 382 k/mm3 | 150–460 k/mm3 | Sodium | 127 mmol/L | 133–145 mmol/L | Potassium | 3.8 mmol/L | 3.8–5.2 mmol/L | Chloride | 88 mmol/L | 98–107 mmol/L | Bicarbonate | 27 mmol/L | 22–29 mmol/L | Anion gap | 12 | 4–17 | BUN | 5 mg/dL | 6–20 mg/dL | Creatinine | 0.6 mg/dL | 0.5–1.0 mg/dL | Serum osmolality | 257 mOsm/kg | 280–290 mOsm/kg | TSH | 1.64 IU/L | 0.4–4.0 IU/L | Free T4 | 1.08 ng/dL | 0.7–1.8 ng/dL | AST | 17 U/L | 0–32 U/L | ALT | 16 U/L | 0–33 U/L | Alkaline phosphatase | 86 U/L | 35–104 U/L | Total bilirubin | 0.5 mg/dL | 0–1.2 mg/dL | Vitamin B12 | 278 pg/mL | 232–1245 pg/mL | Calcium | 9.4 mg/dL | 8.6–10.5 mg/dL | Phosphorous | 3.8 mg/dL | 2.5–4.5 mg/dL | Magnesium | 1.8 mg/dL | 1.6–2.3 mg/dL | Glucose | 117 mg/dL | 70–99 mg/dL | Uric acid | 2.8 mg/dL | 1.6–7.6 mg/dL | Cortisol (7am) | 26 ug/dL | 6–18.4 ug/dL |
| Urinary studies | Urine osmolality | 486 mOsm/kg | 50–1400 mOsm/kg | Urine sodium | 87 mmol/L | 20 mmol/L | Urine barbiturate, cannabinoid, cocaine, benzodiazepine, amphetamine, opiate, oxycodone | Not detected | Not detected |
| Cerebrospinal fluid studies | Opening pressure | 21 cmH20 | <20 cmH20 | Color | Clear | Clear | WBC | 3 | 0–5 | RBC | 1 | 0 | Total protein | 18 mg/dL | 15–60 mg/dL | Glucose | 69 mg/dL | 50–80 mg/dL | Oligoclonal bands | 3 | <5 | IgG index | 0.86 | 0.30–0.77 | Meningoencephalitis PCR panel | Negative | Negative | CSF gram stain and culture | Negative | Negative | CSF AFB smear | Negative | Negative | CSF AFB culture | Negative | Negative | CSF fungal culture | Negative | Negative |
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