Methotrexate-Associated Lymphoproliferative Disorder Developed Ectopically in the Maxillary Gingiva and Bilateral Lungs

Figure 2

Histopathology results. The histopathological diagnosis was EBV-positive diffuse large B-cell lymphoma (DLBCL). (a) H&E stain (×40) showed large numbers of lymphocytes accumulation in the submucosal stroma. (b) H&E stain (×200): lymphocytes accumulation was atypical and large sized with a background of inflammatory cell infiltration. Immunohistochemistry stain (×200): tumor cells showed strong positivity for CD20 (c) and EBER-ISH (d).

(a)

(b)

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