Case Report

Denosumab as the Treatment of Recalcitrant Tuberculous Pleural Effusion-Associated Hypercalcemia

Table 1

Baseline blood investigation.

InvestigationResultsNormal values

Haemoglobin9.3 g/dL13–17
Total white count2.48 × 10^9/L4–10
Platelet167 × 10^9/L150–410
Sodium134 mmol/L135–145
Potassium4 mmol/L3.5–5.1
Urea14.10 mmol/L2.78–8.07
Creatinine212 μmol/L62–106
eGFR26.9 mL/min/1.73 m2>60 mL/min/1.73 m2
Magnesium1.02 mmol/L0.66–0.99
Corrected calcium3.03 mmol/L2.20–2.55
Phosphate1.33 mmol/L0.80–1.45
Total protein83.9 g/L64.0–83.0
Albumin30 g/L35–52
Total bilirubin20 μmol/L<21
Alanine transaminase8 U/L<41
Alkaline phosphate146 U/L40–130
Gamma-glutamyl transferase (GGT)67 U/L<60
Erythrocyte sedimentation rate (ESR)>1201–15
Full blood pictureMacrocytic anemia: macrocytosis of RBC with polychromatic cells and mild rouleaux formation. No blast or abnormal lymphoid/plasmacytoid looking cell.