Case Report
Diagnosis and Management of Acquired Hemophilia A: Case Reports and a Literature Review
Table 2
Summary of recommended inhibitor eradication therapies found in the literature.
| Therapy | Authors | Tiede et al. [16] | Kruse-Jarres et al. [6] | Shetty et al. [17] |
| Corticosteroid | Prednisolone or prednisone 1 mg/kg/day orally for a maximum of 4–6 weeks | Prednisone 1 mg/kg/day orally daily or dexamethasone 40 mg orally daily | Prednisone 1 mg/kg/day orally daily |
| Rituximab | Dose of 375 mg/m2 for a maximum of four cycles | Dose of 375 mg/m2 IV weekly for 4 weeks or dose of 100 mg weekly for 4 weeks | Dose of 375 mg/m2 IV weekly for 4 weeks |
| Cytotoxic agents | Cyclophosphamide 1.5–2 mg/kg/day orally for a maximum of 6 weeks or mycophenolic acid (MMF) 1 g/day for 1 week, followed by 2 g/day | Cyclophosphamide 1-2 mg/kg orally daily or cyclophosphamide ∼5 mg/kg IV for 3-4 weeks | Cyclophosphamide 1-2 mg/kg daily |
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