Case Series
A Case Series of Severe Dengue with Neurological Presentation in Children from a Colombian Hyperendemic Area
Table 2
Hematologic parameters description according to hospitalization day (mean (IQR) [n]).
| | | Parameter | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 |
| | Blood parameters median (IQR) [n = ] | Hemoglobin (mg/dL) | 11.5 (11.2–11.9) [7] | 10.7 (10.3–11.6) [6] | 10.4 (10–10.4) [6] | 11.5 (10.9–12.2) [6] | 10.8 (9.6–12.2) [5] | 11.5 (10.5–13.2) [6] | 11.6 (11.4–12.3) [5] | | Hematocrit (%) | 33.8 (33.5–36.8) [7] | 32.5 (31.1–34.2) [6] | 31.8 (31–32.5) [6] | 33.9 (32.2–35.5) [6] | 32.6 (29.3–35.5) [5] | 34.6 (32.6–39.6) [6] | 33.5 (33.4–35) [5] | | Leukocytes (x 1000 cell/μL) | 9.8 (5.9–13.9) [8] | 7.5 (5.1–8.8) [6] | 6.8 (4.0–11.1) [7] | 3.6 (2.8–4.8) [6] | 5.1 (2.7–6.5) [6] | 5.7 (1.8–8.4) [6] | 8.4 (6.0–7.2) [5] | | Neutrophils (%) | 56 (41–71) [8] | 45.6 (31–60) [6] | 42.5 (30–51) [6] | 36.6 (28–43) [6] | 38.6 (35–51) [6] | 32.6 (18.2–43.4) [6] | 35.8 (32–37) [5] | | Lymphocytes (%) | 33.9 (19.6–46.8) [8] | 47.1 (33–62) [6] | 48.9 (87.9–60.3) [6] | 52.1 (43–69) [6] | 51.8 (36–57) [6] | 53.2 (37–67) [6] | 40.3 (31–56) [5] | | Platelets (x1000 cell/μL) | 184.8 (109–230) [7] | 251.8 (130–372) [7] | 266.8 (180–380) [6] | 199.1(105–207) [6] | 169.2 (88–211) [5] | 99.2 (80–88) [5] | 271.4 (85–457) [5] |
| | Clinical laboratory values mean (SD) [n = ] | PT (seg) | ∗15.4 (2.3) [5] | 13.5 [1] | 13.8 (0.6) [2] | 13.7 (2.7) [3] | 14.2 (1.6) [6] | 12.7 (1.1) [4] | 13.2 (0.5) [3] | | PTT (seg) | ∗35.1 (8.9) [5] | ∗37.9 [1] | 29.8 (2.4) [2] | ∗32.9 (5.6) [3] | ∗32.3 (8.1) [6] | ∗32.66 (5.7) [3] | ∗37.1 (1.0) [4] | | AST (UI/mL) | ∗66.9 (35.9) [3] | ∗78.9 (14.4) [2] | 59.3 [1] | 50.4 (21.1) [3] | ∗82.4 (52.5) [4] | ∗83.1 (43.4) [4] | ∗108.5 (78.1) [2] | | ALT (UI/mL) | 75.9 (96.6) [3] | 90.4 (96.6) [2] | 28.2 (12.4) [2] | 23.4 (6.1) [3] | 35.2 (12.3) [5] | 48.3 (20.9) [4] | 49.5 (18.1) [3] | | BUN (mg/dL) | 4.45 (1.3) [2] | NA | 2.75 (0.4) [2] | NA | 5.4 (6.1) [2] | 3.6 [1] | 9.9 (0.1) [2] | | Creatinine (mg/dL) | 0.29 [3] | 0.38 [1] | 0.27 [2] | 0.2 [1] | 0.36 [3] | 0.27 [1] | 0.52 [1] |
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∗Significant differences between values in different hospitalization days, NA: not available. PT, prothrombin time. PTT, partial thromboplastin time. AST, aspartate transaminase. ALT, alanine aminotransferase. BUN, blood urea nitrogen.
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