Tofacitinib for the Treatment of Severe Interstitial Lung Disease Related to Rheumatoid Arthritis

Figure 1

Clinical course and therapeutic strategy. ILD: interstitial lung disease; MTX: methotrexate; ETA: etanercept; TCZ: tocilizumab; RTX: rituximab; VAS: Visual Analogue Scale; FVC: forced vital capacity; DLCO: diffusing capacity of the lung for carbon monoxide; RA: rheumatoid arthritis; CRP: C-reactive protein; RF: rheumatoid factor; ACPA: anticitrullinated protein antibodies; ANA: antinuclear antibodies; ENA: extractable nuclear antigen; ANCA: antineutrophil cytoplasmic antibodies; DAS-28: disease activity score on 28 joints.