Giant Parathyroid Adenoma-Associated Fracture, Not All Lytic Bone Lesions are Cancer: A Case-Based Review

Figure 2

(a) Chestx-ray showing loss of cortical continuity through the surgical neck of the right proximal humerus with a lytic lesion, suggesting an impacted fracture and cortical alteration of the distalclavicle. (b) Bone scintigraphy with MDP-99 m Tc, shows the abnormal distribution of the radiotracer due to diffuse and generalized uptake increase in the bone system, with a reduction in soft tissues. (c) Proximal right humerus biopsy showing multiple giant osteoclast cells, dispersed among a fibrous stroma with hemorrhagic foci and hemosiderin deposits and scarce osteoid with prominent resorption by osteoclasts indicating compatible with Brown tumor due to hyperparathyroidism.

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