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Author, year | Age (year), Gender, Race | Symptoms at presentation | Relevant comorbidities | G6PDhistory | Hemoglobin (g/dl) | G6PDlevel (IU/g Hg) | Peripheral blood smear | Outcome |
Baseline | crisis |
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Laslett et al. 2021 [8] | 60, male, African American | Fever and dizziness and mild shortness of breath | G6PD | Known | 14.1 | 6.8 | 19.8 | Early red cell precursors and hemighost cells | Expired (hemodynamic compromise) |
|
Ali et al. 2021 [9] | 57, male, African (Nigerian) | COVID-19 and DKA | Diabetes | New | 12.4 | 7.4 | 2.8 | Hemighost cells | NR |
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Palmer et al. 2020 [10] | 62, male, Africocaribbean | Fever, dyspnea, vomiting, and diarrhea | DM type 2 and HTN | New | 16 | 5.2 | 0.8 | Normochromic normocytic erythrocytes and a few hemighost cells | Discharged |
|
Obeidat et al. 2020 [11] | 64, male, NR | Cough and fever | DM, hypothyroidism, and HTN | New | 13.2 | NR | 14 (224–517) | Moderate normochromic, normocytic anemia few ovalocytes, few spherocytes, and mild rouleaux formation with mild neutrophilic leukocytosis with mild absolute lymphopenia | NR |
|
Mastroianni et al. 2020 [12] | 32,male, sub-Saharan African | NR | Nothing | New | 10 | 7.7 | Below 0.2 | No schistocytes or reticulocytosis | Discharged |
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Maillart et al. 2020 [13] | 65, male, African | Hypoxemia | HTN and type 2 diabetes | New | 13.3 | Below detection | Below 0.2 | NR | NR |
|
Kuipers et al. 2020 [14] | 56, male, NR | Myalgia and a dry cough | DM type2 | New | 11.4 | NR | 0.1 | Blister cells | NR |
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Dickinson et al. 2020 [15] | 60, male, African American | Fever and shortness of breath | HTN and type 2 diabetes | New | 12 | 6.8 | Normal | Schistocytes and spherocytes | Expired (refractory shock) |
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Franceschi et al. 2020 [16] | 72, male, Caucasian | Fatigue, dyspnea, dizziness, and fever | Ischemic cardiomyopathy | New | 15 | 12.5 | NR | Anisopoikilocytosis; reticulocytes as large and round-shaped cells; some “hemighost” | NR |
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Beauverd et al. 2020 [17] | 68, male, Congolese | Fever, dyspnea, muscular pain, and tiredness | Type 2 DM, HTN, and chronic renal insufficiency | New | 12 | 6.5 | 2.5 | Numerous hemi-ghost cells and microspherocytes | NR |
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Aguilar et al. 2020 [18] | 51, male, African American | Fevers, myalgia, and dry cough, and worsening shortness of breath | Type 2 DM, HTN, and morbid obesity | New | 14.5 | 5.9 | Abnormal | Positive schistocyte | Discharged |
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