Fever, Haematuria, and Acute Graft Dysfunction in Renal Transplant Recipients Secondary to Adenovirus Infection: Two Case Reports
Renal graft biopsies. In case 1, histological findings were irrelevant; no viral inclusions were identified by light microscopy (H&E (a) and (b)) or immunohistochemistry. Renal biopsy of case 2 demonstrated focal interstitial necrotizing granulomata with neutrophils, plasma cells, and lymphocytes ((c) H&E and (d) PAS stain); note that the glomeruli are not affected. Control graft biopsy only demonstrated minimal interstitial fibrosis ((e) PAS stain and (f) Masson trichromic stain).
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