Case Report
A Retrospectively Diagnosed Case of IgG4-Related Tubulointerstitial Nephritis Showing Good Renal Outcome and Pathological Progress
Table 1
Clinical parameters at the first and second renal biopsy and at the final followup.
| | Reference range | First biopsy | Second biopsy | Final followup |
| Hb (g/dL) | 13.5–17.5 | 10.3 | 13.8 | 13.9 | Serum TP (g/dL) | 6.5–8.0 | 10.5 | 7.2 | 8.1 | Serum Alb (g/dL) | 3.9–4.8 | 3.2 | 3.8 | 3.9 | Serum Cr (mg/dL) | 0.5–1.1 | 1.3 | 0.9 | 1.01 | ESR (mm/h) | 0–15 | 127 | ND | ND | Serum IgG (mg/dL) | 870–1700 | 6530 | 1599 | 1974 | Serum IgG4 (mg/dL) | 4.8–105 | ND | 532 | 466 | Serum IgA (mg/dL) | 110–350 | 92 | 138 | 190 | Serum IgM (mg/dL) | 30–180 | 86 | 119 | 147 | CH50 (U/mL) | 25.0–48.0 | <10.0 | 49 | ND | Serum C3c (mg/dL) | 85–160 | 18 | 68 | 80.8 | Serum C4 (mg/dL) | 15–40 | <7.2 | 23.2 | 21.3 | Serum C1qIC (g/mL) | <3.0 | 34.7 | ND | ND | Serum IL-2R (U/mL) | 220–530 | 2540 | 624 | 811 | Serum BMG (mg/L) | 0.5–1.7 | 5.15 | 1.88 | ND | Urine BMG (mg/L) | <0.25 | 0.04 | 0.15 | 0.17 | ANA | Negative | 1280-fold | ND | ND | Urine protein (g/24 h) | <0.05 | 0.07 | 0.07 | ND | Urine NAG (U/L) | <11.0 | 27.7 | 5.8 | ND |
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Hb: hemoglobin; TP: total protein; Alb: albumin; Cr: creatinine; ESR: erythrocyte sedimentation rate; CH50: total serum hemolytic activity; C3c: complement 3c; C4: complement 4; C1qIC: C1q binding immune complex; BMG: beta2-microglobulin; ANA: antinuclear antibody; NAG: N-acetyl-beta-D-glucosaminidase; ND: not done.
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