Amiloride as an Alternate Adjuvant Antiproteinuric Agent in Fabry Disease: The Potential Roles of Plasmin and uPAR
Figure 2
Interactions between globotriaosylceramide (GL-3), uPAR, plasminogen/plasmin, and integrin αvβ3 and the development of proteinuria in Fabry disease, counteracted by amiloride.